Enjoyable Gut Neuroscience

• Monro, R.L., Bornstein, J.C. and Bertrand, P.P. (2008). Synaptic Transmission from the Submucous Plexus to the Myenteric Plexus in Guinea-Pig Ileum. Neurogastroenterology and Motility. In press. doi: 10.1111/j.1365-2982.2008.01157.x
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• Bertrand, P.P. and Bian, X.-C. (2008). From 'macro' to 'micro': mapping the neuronal circuits of the intestine. Clinical and Experimental Pharmacology and Physiology. Jul;35(7):715-6.
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• Ren, J. and Bertrand, P.P. (2007). Purinergic receptors and synaptic transmission. Purinergic Signalling. DOI 10.1007/s11302-007-9088-5.
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• Bertrand P.P. (2007). A new role for P2 receptors: talking with calcium-activated potassium channels. Neurogastroenterol Motil. 19(11):865-8.
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• Bertrand, P.P. and Bertrand R.L. (2007). Teaching basic gastrointestinal physiology using classic papers by Dr. Walter B Cannon. Advances in Physiology Education. 31(2):136-9.
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• Bertrand, P.P. (2006). Real-time measurement of serotonin release and motility in guinea pig ileum. Journal of Physiology. 577(2): 689-704.
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• Bertrand, P.P., Paranavitane, U.T., Chavez, C., Gogos, A., Jones, M. and van den Buuse, M. (2005). The effect of low oestrogen state on serotonin transporter function in mouse hippocampus: a behavioural and electrochemical study. Brain Research. 1064(1-2): 10-20.
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• Monro, R.L., Bornstein, J.C. and Bertrand, P.P. (2005). Slow excitatory post-synaptic potentials in myenteric AH neurons of the guinea-pig ileum are reduced by the 5-hydroxytrytamine7 receptor antagonist SB 269970. Neuroscience. 134(3): 975-986.
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• Bertrand, P.P. and Thomas, E.A. (2004). Multiple Levels of Sensory Integration in the Intrinsic Sensory Neurons of the Enteric Nervous System. Clin Exp Pharmacol Physiol, 31(11):745-55. Review.
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• Bertrand, P.P. (2004). Real-time detection of serotonin release from enterochromaffin cells of the guinea pig ileum. Neurogastroenterology and Motility, 16(5): 511–514.
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• Bertrand, P.P. (2004). Bursts of recurrent excitation in the activation of intrinsic sensory neurons of the intestine. Neuroscience, 128(1): 51-63.
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• Bian, X.-C., Heffer, L.F., Gwynne, R.M., Bornstein, J.C. and Bertrand, P.P. (2004). Synaptic transmission in simple motility reflex pathways of guinea pig distal colon. American Journal of Physiology, 287: G1017–G1027
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• Monro, R.L., Bertrand, P.P. and Bornstein, J.C. (2004). ATP participates in three excitatory post-synaptic potentials in the submucous plexus of the guinea pig ileum. Journal of Physiology, 556(2): 571-584.
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• Bertrand, P.P. (2003). ATP and Sensory Transduction in the Enteric Nervous System. The Neuroscientist, 9(4):243-60. Review.
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• Bian, X.-C., Bornstein, J.C. and Bertrand, P.P. (2003). Nicotinic transmission at functionally distinct synapses in descending reflex pathways of the rat colon. Neurogastroenterology and Motility, 15(2):161-71.
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• Monro, R.L., Bertrand, P.P. and Bornstein, J.C. (2002). ATP and 5-HT are the principal neurotransmitters in the descending excitatory reflex pathway of the guinea-pig ileum. Neurogastroentrology and Motility. 14(3):255-264
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• Bertrand P.P. and Bornstein J.C. (2002) ATP as a putative sensory mediator: activation of intrinsic sensory neurons of the myenteric plexus via P2X receptors. Journal of Neuroscience. 22(12):4767–4775.
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• Bornstein J.C., Furness J.B., Kunze W.A., and Bertrand P.P. (2002). Enteric Reflexes that Influence Motility. In "Innervation of the Gastrointestinal Tract". eds Costa, M. & Brookes, S.H. pp. 1-55. London: Taylor & Francis.
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• Lomax, A.E.G., Bertrand, P.P. and Furness, J.B. (2001) Electrophysiological characteristics distinguish three classes of neuron in submucosal ganglia of the guinea-pig distal colon. Neuroscience. 103(1): 247-257.
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• Bertrand, P.P., Kunze, W.A.A., Furness, J.B. and Bornstein, J.C. (2000) The terminals of myenteric intrinsic primary afferent neurons of the guinea pig ileum are excited by 5-HT acting at 5-HT₃ receptors. Neuroscience. 101(2):459-469.
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• Bian, X.-C., Bertrand, P.P. and Bornstein, J.C. (2000) Descending inhibitory reflexes involve P2X receptor-mediated transmission from interneurons to motor neurons in guinea-pig ileum. Journal of Physiology. 528(Pt 3):551-560.
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• Thomas, E.A., Bertrand, P.P, Bornstein, J.C. (2000) A computer simulation of recurrent, excitatory networks of sensory neurons of the gut. Neuroscience Letters. 287(2):137-140
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• Bian, X-C, Bertrand PP and Bornstein JC. (2000) Evidence for functional NK1-tachykinin receptors on motor neurons supplying the circular muscle of guinea-pig small and large intestine. Neurogastroenterology and Motility. 12(4):307-15.
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• Bertrand, P.P., Bornstein, J.C. (2000). ATP and 5-HT activate intrinsic sensory neurons of the intestine. Falk Symposium #112 - Neurogastroenterology: From Clinics to Basics. Ed.s Krammer and Singer. 172-189.
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• Bertrand, P.P., Thomas, E.A., Kunze, W.A.A. and Bornstein, J.C. (2000) A simple mathematical model of ongoing slow excitatory post-synaptic potentials in enteric neurons. Journal Computational Neuroscience. 8(2):127-142
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• Thomas, E. A., Bertrand, P.P. and Bornstein, J. C. (1999). Genesis and role of coordinated firing in a feed forward network - a model study of the enteric nervous system. Neuroscience 1999;93(4):1525-37.
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• Kunze WA, Clerc N, Bertrand PP Furness JB. (1999). Contractile activity in intestinal muscle evokes action potential discharge in guinea-pig myenteric neurons. Journal of Physiology. 517(Pt 2):547-561.
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• Lomax AE, Sharkey KA, Bertrand PP, Low AM, Bornstein JC, Furness JB. (1999). Correlation of morphology, electrophysiology and chemistry of neurons in the myenteric plexus of the guinea-pig distal colon. J Auton Nerv Syst. 76(1):45-61.
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• Clerc N, Furness JB, Kunze WA, Thomas EA, Bertrand PP. (1999). Long-term effects of synaptic activation at low frequency on excitability of myenteric AH neurons. Neuroscience. 90(1):279-89.
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• Clark MJ, Wright T, Bertrand PP, Bornstein JC, Jenkinson KM, Verlinden M, Furness JB. (1999). Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum. Clin Exp Pharmacol Physiol. 26(3):242-5.
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• Furness JB, Clark MJ, Wright T, Bertrand PP, Bornstein JC, Verlinden M. (1999). An action of erythromycin in the intestine that is not mediated via motilin receptors. Clin Exp Pharmacol Physiol. 26(2):100-4.
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• Bertrand PP, Kunze WA, Bornstein JC, Furness JB. Electrical mapping of the projections of intrinsic primary afferent neurones to the mucosa of the guinea-pig small intestine. Neurogastroenterol Motil. 1998 Dec;10(6):533-41.
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• Sharkey KA, Lomax AE, Bertrand PP, Furness JB. Electrophysiology, shape, and chemistry of neurons that project from guinea pig colon to inferior mesenteric ganglia. Gastroenterology. 1998 Oct;115(4):909-18.
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• Lomax AE, Bertrand PP, Furness JB. Identification of the populations of enteric neurons that have NK1 tachykinin receptors in the guinea-pig small intestine. Cell Tissue Res. 1998 Oct;294(1):27-33.
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• Kunze WA, Furness JB, Bertrand PP, Bornstein JC. Intracellular recording from myenteric neurons of the guinea-pig ileum that respond to stretch. J Physiol (Lond). 1998 Feb 1;506 ( Pt 3):827-42.
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• Furness JB, Kunze WA, Bertrand PP, Clerc N, Bornstein JC. Intrinsic primary afferent neurons of the intestine. Prog Neurobiol. 1998 Jan;54(1):1-18. Review.
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• Bertrand PP, Kunze WA, Bornstein JC, Furness JB, Smith ML. Analysis of the responses of myenteric neurons in the small intestine to chemical stimulation of the mucosa. Am J Physiol. 1997 Aug;273(2 Pt 1):G422-35.
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• Bornstein JC, Furness JB, Kelly HF, Bywater RA, Neild TO, Bertrand PP. Computer simulation of the enteric neural circuits mediating an ascending reflex: roles of fast and slow excitatory outputs of sensory neurons. J Auton Nerv Syst. 1997 Jun 6;64(2-3):143-57.
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• Kunze WA, Bertrand PP, Furness JB, Bornstein JC. Influence of the mucosa on the excitability of myenteric neurons. Neuroscience. 1997 Jan;76(2):619-34.
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• Furness JB, Bornstein JC, Kunze WA, Bertrand PP, Kelly H, Thomas EA. Experimental basis for realistic large-scale computer simulation of the enteric nervous system. Clin Exp Pharmacol Physiol. 1996 Sep;23(9):786-92. Review.
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• Bertrand PP, Galligan JJ. Signal-transduction pathways causing slow synaptic excitation in guinea pig myenteric AH neurons. Am J Physiol. 1995 Nov;269(5 Pt 1):G710-20.
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• Galligan JJ, Bertrand PP. ATP mediates fast synaptic potentials in enteric neurons. J Neurosci. 1994 Dec;14(12):7563-71.
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• Bertrand PP, Galligan JJ. Contribution of chloride conductance increase to slow EPSC and tachykinin current in guinea-pig myenteric neurones. J Physiol (Lond). 1994 Nov 15;481 ( Pt 1):47-60.
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• Bertrand PP, Galligan JJ. Alfaxalone, pentobarbital and diazepam potentiate gamma-aminobutyric acid-induced depolarizations in single myenteric neurons of guinea pig intestine. J Pharmacol Exp Ther. 1992 Aug;262(2):677-82.
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